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A calmodulin inhibitor, W-7 influences the effect of cyclic adenosine 3', 5'-monophosphate signaling on ligninolytic enzyme gene expression in Phanerochaete chrysosporium
Takaiku Sakamoto, Yuki Yao, Yoshifumi Hida, Yoichi Honda, Takashi Watanabe, Wataru Hashigaya, Kazumi Suzuki, Toshikazu Irie
AMB Express , 2012, DOI: 10.1186/2191-0855-2-7
Abstract: White-rot fungi are known to have a powerful ligninolytic system that can completely degrade wood lignin (Kirk and Farrell 1987; Kirk et al. 1975) as well as persistent organic pollutants such as dioxin (Bumpus et al. 1985). This ability may be applicable to the construction of a novel potent bioreactor system to convert wood to potent materials and energy sources with low environmental load and to bioremediate polluted environments. However, the ligninolytic property of these fungi is attributable to many known and unknown enzyme genes, expression of which is inductive, and the factors that determine this expression are not completely understood. The lack of knowledge regarding the ligninolytic property of these fungi is an impediment to the development of a highly effective lignin-degrading fungal strain for the construction of an efficient bioreactor system (Cullen and Kersten 2004). The identification of a master regulator that regulates the entire ligninolytic system in white-rot fungi could be used as a target for breeding a high lignin-degrading strain and for furthering our understanding of the lignin-degradation system in these fungi.Phanerochaete chrysosporium, which is the most widely researched white-rot fungus in the world, has 2 families of lignin-degrading peroxidases designated lignin peroxidase (LiP) and manganese peroxidase (MnP) (Heinzkill and Messner 1997). LiP and MnP are thought to play an important role in initiating the lignin degrading reaction of the fungus, because they can cleave lignin structures extracellularly in the first step of lignin mineralization (Cullen and Kersten 2004; Gold et al. 1984; Tien and Kirk 1984). Moreover, LiP and MnP themselves also have potential applications in treating textile effluent (Sedighi et al. 2009; Singh et al. 2010). However, their expression is inductive, related to unknown factors, and known to be unstable, as is the entire ligninolytic system. Information concerning the LiP and MnP expression system
The Home Market Effect under Constant Returns and Monopolistic Competition  [PDF]
Wataru Johdo
Theoretical Economics Letters (TEL) , 2012, DOI: 10.4236/tel.2012.25082
Abstract: Most existing theoretical studies on home market effects depend crucially on the assumption of increasing returns to scale technology. This paper studies the consequences of the absence of increasing returns to scale on home market effects by employing a constant returns monopolistic competition model. This paper demonstrates that home market effects can emerge or disappear depending on the magnitude of the elasticity of substitution and transport costs even in the constant returns model with firm mobility. In particular, a reverse home market effect can result when the elasticity of substitution is low and transport costs are high.
Asymmetric Transportation Costs and the Home Market Effect  [PDF]
Wataru Johdo
Theoretical Economics Letters (TEL) , 2013, DOI: 10.4236/tel.2013.32013
Abstract:

Most existing theoretical studies on home market effects depend crucially on assumptions of symmetric transportation costs and increasing returns to scale technology. In our model, we remove the home market effect assumptions from the main model used in the literature. Instead, this paper employs a constant returns monopolistic competition model with asymmetric transportation costs. We show that 1) when the home country’s transportation cost is large enough for a given level of the foreign country’s transportation cost, the HME appears in the home country, and 2) the opposite of the HME is observed in the home country as long as the foreign country’s transportation cost is large enough for a given level of the home country’s transportation cost.

Consumption Tax, Nontraded Goods and Welfare  [PDF]
Wataru Johdo
Theoretical Economics Letters (TEL) , 2013, DOI: 10.4236/tel.2013.35044
Abstract: This paper studies the welfare effects of a consumption tax rise based on the two-sector small open economy model of Obstfeld and Rogoff (1995) and Lane (1997). The main findings of our analysis are that 1) in the case of free trade, the consumption tax rise has no effect on welfare, 2) when there is the nontraded goods sector, the consumption tax rise has a negative effect on welfare, and 3) the larger the share of nontraded goods in consumption is, the larger the negative welfare effect of consumption tax will be.
On the Predictive Ability of Geomagnetic Disturbances from Solar Wind Measurements at Separated Solar Longitude  [PDF]
Wataru Miyake, Tsutomu Nagatsuma
International Journal of Astronomy and Astrophysics (IJAA) , 2012, DOI: 10.4236/ijaa.2012.22009
Abstract: In-situ solar wind measurement at a solar longitude separated from the earth in interplanetary space is expected to provide a great progress in practical space weather forecast, which has been confirmed by some recent studies. We introduce geoeffective solar wind conditions in correlation analysis between STEREO and ACE measurements. We sort solar wind data of ACE by using geomagnetic condition, and evaluate actual ability for predicting geoeffective solar wind arrival at ACE from STEREO-A and B solar wind measurement, by assuming simple corotating structures in interplanetary space. The results show that geomagnetic disturbances are more difficult to be predicted than quiet intervals, suggesting that the simple correlation method of solar wind measurement at separated solar longitude is not enough for accurately predicting geomagnetic disturbances, even though the correlation seems generally high. Although in-situ solar wind monitoring at a vantage point trailing behind the earth would definitely improve the prediction capability of solar wind structure arriving at the terrestrial plasma environment, we emphasize that the predictive ability of geoeffective disturbances would still remain low. We suggest that more sophisticated prediction schemes should be developed.
Augmentation of protective immune responses against viral infection by oral administration of schizophyllan
Wataru Itoh
Mediators of Inflammation , 1997, DOI: 10.1080/09629359791596
Abstract:
Management of chronic disruption of the distal tibiofibular syndesmosis
Wataru Miyamoto
World Journal of Orthopedics , 2011, DOI: 10.5312/wjo.v2.i1.1
Abstract: Disruption of the distal tibiofibular syndesmosis is frequently accompanied by rotational ankle fracture such as pronation-external rotation and rarely occurs without ankle fracture. In such injury, not only inadequately treated or misdiagnosed cases, but also correctly diagnosed cases can possibly result in a chronic pattern which is more troublesome to treat than an acute pattern. This paper reviews anatomical and biomechanical characteristics of the distal tibiofibular joint, the mechanism of chronic disruption of the distal tibiofibular syndesmosis, radiological and arthroscopic diagnosis, and surgical treatment.
A Design of Parameter Optimal Iterative Learning Control for Linear Discrete-Time Systems
Wataru Kase
ISRN Applied Mathematics , 2014, DOI: 10.1155/2014/816860
Abstract: The iterative learning control algorithm proposed by Owens and Feng, which guarantees the monotonic convergence of the tracking error norms along with the trial, will be modified. The learning gain of the proposed method will be determined through a quadratic cost function. MIMO plant case will be also discussed. Numerical simulations will be presented to confirm the validity of the proposed design. 1. Introduction The iterative learning control (ILC) proposed by Kawamura et al. [1] is a method to control systems operating in a repetitive mode. Examples of such systems include robot manipulator and chemical batch processes reliability testing rigs. The control purpose of ILC is to follow a specified trajectory with high precision. Unlike model matching method [2, 3], it might be useful for the plant with nonminimum phase property. There are many approaches to ILC in the literature [4–6], for example, the method based on the PD control [1], the inverse systems [7–9], control [10, 11], and so on. Although the convergence properties of these algorithms have been analyzed, it is not always clear how to choose the free parameters of the algorithms to attain fast or monotonic convergence. Owens and Feng [12] used parameter optimization through a quadratic cost function as a method to establish the ILC law. The important feature of the algorithm is that the learning gain is to be varied in each trial. The method guarantees the monotonic convergence of tracking error to zero, if a given plant satisfies a definite condition [12]. In the case of nondefinite plants, the behavior of the method was discussed in [13]. In this paper, the method by Owens and Feng will be modified for nondefinite plants. The learning gain is not only for each trial, but also varied at each step. With such modifications, it can be useful for nondefinite plants. Moreover, a special analysis for the tracking error will be shown. The paper is organized as follows. In the next section, the problem statement will be presented and brief review of the method by Owens and Feng will be given. A derivation of the modified learning gain and error analysis with the proposed gain will be presented in Section 3. A determination of the gain matrix will be shown in Section 4. The paper was a modified version of the conference paper, and the most different part will be given in Section 5, that is, an extension to the multi-input, multioutput systems. Some simulation results will be given in Section 6 to confirm the effectiveness of the proposed method. Concluding remarks will be given in Section 7. 2.
Mathematical Remarks on the Feynman Path Integral for Nonrelativistic Quantum Electrodynamics
Wataru Ichinose
Physics , 2008,
Abstract: The Feynman path integral for nonrelativistic quantum electrodynamics is studied mathematically of a standard model in physics, where the electromagnetic potential is assumed to be periodic with respect to a large box and quantized thorough its Fourier coefficients. In physics, the Feynman path integral for nonrelativistic quantum electrodynamics is defined very formally. For example, as is often seen, even independent variables are not so clear. First, the Feynman path integral is defined rigorously under the constraints familiar in physics. Secondly, the Feynman path integral is also defined rigorously without the constraints, which is stated in Feynman and Hibbs' book without any comments. So, our definition may be completely new. Thirdly, the vacuum and the state of photons of momentums and polarization states are expressed by means of concrete functions of variables consisting of the Fourier coefficients of the electromagnetic potential. Our results above have many applications as is seen in Feynman and Hibbs' book, though the applications are not rigorous so far. It is also proved rigorously by means of the distribution theory that the Coulomb potentials between charged particles naturally appear in the Feynman path integral above. As is well known, this shows that photons give the Coulomb forth.
Gauge and Cutoff Function Dependence of the Ultraviolet Fixed Point in Quantum Gravity
Wataru Souma
Physics , 2000,
Abstract: The exact renormalization group equation for pure quantum gravity is derived for an arbitrary gauge parameter in the space-time dimension $d=4$. This equation is given by a non-linear functional differential equation for the effective average action. An action functional of the effective average action is approximated by the same functional space of the Einstein-Hilbert action. From this approximation, $\beta$-functions for the dimensionless Newton constant and cosmological constant are derived non-perturbatively. These are used for an analysis of the phase structure and the ultraviolet non-Gaussian fixed point of the dimensionless Newton constant. This fixed point strongly depends on the gauge parameter and the cutoff function. However, this fixed point exists without these ambiguities, except for some gauges. Hence, it is possible that pure quantum gravity in $d=4$ is an asymptotically safe theory and non-perturbatively renormalizable.
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